Are there any investments that I can’t make with my self-directed IRA?

You cannot invest in Life Insurance Contracts or Collectibles (as defined by the IRS). Also, you may not participate in prohibited transactions. As an self directed IRA owner, if you violate these rules, you may forfeit your entire IRA. There are many self directed IRA rules and stipulations, so it is important that you work with competent advisors to help you avoid such transactions.